Pancreatic function test
This test measures the ability of the pancreas to respond to
secretin, a hormone produced by the small intestine when partially digested food has moved
into the intestine from the stomach.
Secretin normally stimulates the pancreas to secrete a fluid with a high concentration
of bicarbonate. Acting as an antacid, this bicarbonate fluid neutralizes the acidity of
the material from the stomach so that enzymes in the small intestine can function properly
in the breakdown of food and absorption of nutrients.
Why is a Pancreatic function test performed
The secretin stimulation test is performed to evaluate the
function of the pancreas in digestion. People with diseases involving the pancreas such as
chronic pancreatitis , cystic fibrosis, or pancreatic cancer may have abnormal pancreatic
function.
The bodies of people with cystic fibrosis form mucous plugs that can obstruct the
pancreatic ducts that empty into the small intestines. These plugs prevent neutralization
of the food acidity, which ultimately reduces the ability to digest and absorb foods. |